Given the events of Beyond the Alley of the Dolls’ alternate futures, The Narrator’s coomments, and from the looks of The City That Dares Not Sleep, I wanna say that prolly either Sam, Max, or both will meet a terrible fate. Even if they do, though, they’ll prolly come back alive the way they did in Night of the Raving Dead, or how Guybrush did in Rise of the Pirate God.